Product Data Sheet
Lumateperone-d4
Catalog No. A29365
Lumateperone-d4 is a deuterium-labeled analog of Lumateperone, primarily targeting the 5-HT2A receptor as an antagonist (Ki = 0.54 nM). It exhibits dual action as a partial agonist at presynaptic D2 receptors and an antagonist at postsynaptic D2 receptors (Ki = 32 nM), along with modulation of dopamine D1 receptors. This compound is valuable for investigating schizophrenia, bipolar depression, and has demonstrated anticancer properties, making it a versatile tool in chemical research.
Chemical Information
| Catalog Num | A29365 |
|---|---|
| M. Wt | 397.52 |
| Formula | C24H24D4FN3O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2102683-55-4 |
| Synonyms | ITI-007-d4 |
| SMILES | CN1C2=C3C([C@@]4([H])[C@@](CCN(C4)CCCC(C5=CC=C(C=C5)F)=O)([H])N3C([2H])([2H])C1([2H])[2H])=CC=C2 |
Biological Activity
| Description | Lumateperone-d4 is a deuterium-labeled analog of Lumateperone, primarily targeting the 5-HT2A receptor as an antagonist (Ki = 0.54 nM). It exhibits dual action as a partial agonist at presynaptic D2 receptors and an antagonist at postsynaptic D2 receptors (Ki = 32 nM), along with modulation of dopamine D1 receptors. This compound is valuable for investigating schizophrenia, bipolar depression, and has demonstrated anticancer properties, making it a versatile tool in chemical research. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
