Product Data Sheet

KF 18259

Catalog No. A29386

main product photo
KF 18259 is a potent antagonist of the 5-HT3 receptor. It effectively inhibits propulsive motility in both the proximal and distal colon induced by wrap-restraint stress. This compound is valuable for research into gastrointestinal motility disorders and the role of serotonin receptors in stress-related gastrointestinal functions.
Chemical Information
Catalog NumA29386
M. Wt404.93
FormulaC22H29ClN2O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.139094-48-7
Synonyms
SMILESCN([C@@H](CC1)C2)[C@H]1C[C@@H]2OC(C(C3=CC=CC=C3N4CC(C)C)=CC4=O)=O.Cl
Biological Activity
DescriptionKF 18259 is a potent antagonist of the 5-HT3 receptor. It effectively inhibits propulsive motility in both the proximal and distal colon induced by wrap-restraint stress. This compound is valuable for research into gastrointestinal motility disorders and the role of serotonin receptors in stress-related gastrointestinal functions.
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SHIPPING AND STORAGE
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