Product Data Sheet
Cinanserin
Catalog No. A29392
Cinanserin is a potent and selective antagonist of the 5-HT2 receptor, exhibiting Ki values of 41 nM for 5-HT2 and 3500 nM for the 5-HT1 receptor. Additionally, it acts as an inhibitor of the SARS-CoV 3CLpro, demonstrating KD values of 49.4 µM and 18.2 µM against SARS-CoV 3CLpro and HCoV-229E 3CLpro, respectively. Cinanserin has been shown to effectively reduce systemic burn edema levels, making it valuable for research in neuropharmacology and viral pathogenesis.
Chemical Information
| Catalog Num | A29392 |
|---|---|
| M. Wt | 340.48 |
| Formula | C20H24N2OS |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1166-34-3 |
| Synonyms | |
| SMILES | O=C(NC1=CC=CC=C1SCCCN(C)C)/C=C/C2=CC=CC=C2 |
Biological Activity
| Description | Cinanserin is a potent and selective antagonist of the 5-HT2 receptor, exhibiting Ki values of 41 nM for 5-HT2 and 3500 nM for the 5-HT1 receptor. Additionally, it acts as an inhibitor of the SARS-CoV 3CLpro, demonstrating KD values of 49.4 µM and 18.2 µM against SARS-CoV 3CLpro and HCoV-229E 3CLpro, respectively. Cinanserin has been shown to effectively reduce systemic burn edema levels, making it valuable for research in neuropharmacology and viral pathogenesis. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
