Product Data Sheet

WAY 163909 hydrochloride

Catalog No. A29407

main product photo
WAY 163909 hydrochloride is a selective agonist of the 5-hydroxytryptamine receptor 2C (5-HT2C) with an EC50 of 8 nM and maximum efficacy reaching 90%. Exhibiting minimal interaction with 5-HT2A receptors, it demonstrates a Ki value of 10.5 nM for 5-HT2C, while showing much higher Ki values of 212 nM for 5-HT2A, 343 nM for 5-HT7, and 485 nM for 5-HT2B. This specificity makes it a valuable tool for studying the physiological and pharmacological roles of the 5-HT2C receptor in various biological systems.
Chemical Information
Catalog NumA29407
M. Wt250.77
FormulaC14H19ClN2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.428868-35-3
Synonyms
SMILES[H][C@@]1(CCC2)[C@@]2([H])C3=CC=CC4=C3N1CCNC4.Cl
Biological Activity
DescriptionWAY 163909 hydrochloride is a selective agonist of the 5-hydroxytryptamine receptor 2C (5-HT2C) with an EC50 of 8 nM and maximum efficacy reaching 90%. Exhibiting minimal interaction with 5-HT2A receptors, it demonstrates a Ki value of 10.5 nM for 5-HT2C, while showing much higher Ki values of 212 nM for 5-HT2A, 343 nM for 5-HT7, and 485 nM for 5-HT2B. This specificity makes it a valuable tool for studying the physiological and pharmacological roles of the 5-HT2C receptor in various biological systems.
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