Product Data Sheet
N-Desmethyl Zolmitriptan
Catalog No. A29453
N-Desmethyl Zolmitriptan is an active metabolite that selectively targets the serotonin (5-HT) receptor subtypes 5-HT1B and 5-HT1D. It acts as an agonist of the 5-HT1B receptor, facilitating vasoconstriction in isolated human cerebral arteries, with an EC50 of approximately 100 nM. This compound is valuable for research into migraine mechanisms and the exploration of serotonin signaling pathways.
Chemical Information
| Catalog Num | A29453 |
|---|---|
| M. Wt | 273.33 |
| Formula | C₁₅H₁₉N₃O₂ |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 139264-35-0 |
| Synonyms | 183C91; DZT |
| SMILES | CNCCC1=CNC2=C1C=C(C[C@@H](CO3)NC3=O)C=C2 |
Biological Activity
| Description | N-Desmethyl Zolmitriptan is an active metabolite that selectively targets the serotonin (5-HT) receptor subtypes 5-HT1B and 5-HT1D. It acts as an agonist of the 5-HT1B receptor, facilitating vasoconstriction in isolated human cerebral arteries, with an EC50 of approximately 100 nM. This compound is valuable for research into migraine mechanisms and the exploration of serotonin signaling pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
