Product Data Sheet
ICI 169369 free base
Catalog No. A29458
ICI 169369 free base is a selective and non-competitive antagonist of the 5-HT receptor. This compound effectively diminishes vasopressin responses to insulin-induced hypoglycemia without affecting ACTH, prolactin, or growth hormone release. ICI 169369 also modulates centrally mediated 5-HT activity and has been shown to reduce portal pressure in portal hypertensive models, making it a valuable tool for research in neuroendocrine regulation and vascular physiology.
Chemical Information
| Catalog Num | A29458 |
|---|---|
| M. Wt | 308.44 |
| Formula | C19H20N2S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 85273-95-6 |
| Synonyms | |
| SMILES | CN(C)CCSC1=NC2=CC=CC=C2C=C1C3=CC=CC=C3 |
Biological Activity
| Description | ICI 169369 free base is a selective and non-competitive antagonist of the 5-HT receptor. This compound effectively diminishes vasopressin responses to insulin-induced hypoglycemia without affecting ACTH, prolactin, or growth hormone release. ICI 169369 also modulates centrally mediated 5-HT activity and has been shown to reduce portal pressure in portal hypertensive models, making it a valuable tool for research in neuroendocrine regulation and vascular physiology. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
