Tiospirone
Catalog No. A29466

Tiospirone is a potent 5-HT2 receptor antagonist, demonstrating additional affinity for D2, 5-HT1A, 5-HT7, and sigma receptors. This compound has been shown to decrease ethanol consumption while enhancing food intake in rat models. Additionally, Tiospirone can diminish the reinforcing effects of cocaine, as evidenced in the conditioned place preference paradigm, making it a valuable tool for research into addiction and feeding behavior.
Chemical Information
| Catalog Num | A29466 |
|---|---|
| M. Wt | 440.60 |
| Formula | C24H32N4O2S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 87691-91-6 |
| Synonyms | BMY 13859-1 free base |
| SMILES | O=C1N(CCCCN2CCN(CC2)C3=NSC4=C3C=CC=C4)C(CC5(CCCC5)C1)=O |
Biological Activity
| Description | Tiospirone is a potent 5-HT2 receptor antagonist, demonstrating additional affinity for D2, 5-HT1A, 5-HT7, and sigma receptors. This compound has been shown to decrease ethanol consumption while enhancing food intake in rat models. Additionally, Tiospirone can diminish the reinforcing effects of cocaine, as evidenced in the conditioned place preference paradigm, making it a valuable tool for research into addiction and feeding behavior. |
|---|
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


