Product Data Sheet

Tiospirone

Catalog No. A29466

main product photo
Tiospirone is a potent 5-HT2 receptor antagonist, demonstrating additional affinity for D2, 5-HT1A, 5-HT7, and sigma receptors. This compound has been shown to decrease ethanol consumption while enhancing food intake in rat models. Additionally, Tiospirone can diminish the reinforcing effects of cocaine, as evidenced in the conditioned place preference paradigm, making it a valuable tool for research into addiction and feeding behavior.
Chemical Information
Catalog NumA29466
M. Wt440.60
FormulaC24H32N4O2S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.87691-91-6
SynonymsBMY 13859-1 free base
SMILESO=C1N(CCCCN2CCN(CC2)C3=NSC4=C3C=CC=C4)C(CC5(CCCC5)C1)=O
Biological Activity
DescriptionTiospirone is a potent 5-HT2 receptor antagonist, demonstrating additional affinity for D2, 5-HT1A, 5-HT7, and sigma receptors. This compound has been shown to decrease ethanol consumption while enhancing food intake in rat models. Additionally, Tiospirone can diminish the reinforcing effects of cocaine, as evidenced in the conditioned place preference paradigm, making it a valuable tool for research into addiction and feeding behavior.
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SHIPPING AND STORAGE
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