Product Data Sheet
NPS ALX Compound 4a dihydrochloride
Catalog No. A29480
NPS ALX Compound 4a dihydrochloride is a highly potent and selective antagonist of the 5-hydroxytryptamine 6 (5-HT6) receptor, demonstrating an IC50 of 7.2 nM and a Ki of 0.2 nM. This compound is valuable for research applications targeting neuropsychiatric disorders, where modulation of 5-HT6 receptor activity may be of therapeutic interest. Its specificity and potency make it an essential tool for elucidating the role of the 5-HT6 receptor in various biological processes.
Chemical Information
| Catalog Num | A29480 |
|---|---|
| M. Wt | 504.47 |
| Formula | C25H27Cl2N3O2S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1781934-44-8 |
| Synonyms | |
| SMILES | O=S(N1C=CC2=C1C=C(N3CC(CCC4)N4CC3)C=C2)(C5=C6C=CC=CC6=CC=C5)=O.[H]Cl.[H]Cl |
Biological Activity
| Description | NPS ALX Compound 4a dihydrochloride is a highly potent and selective antagonist of the 5-hydroxytryptamine 6 (5-HT6) receptor, demonstrating an IC50 of 7.2 nM and a Ki of 0.2 nM. This compound is valuable for research applications targeting neuropsychiatric disorders, where modulation of 5-HT6 receptor activity may be of therapeutic interest. Its specificity and potency make it an essential tool for elucidating the role of the 5-HT6 receptor in various biological processes. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
