Product Data Sheet
LEK 8804
Catalog No. A29482
LEK 8804 is a selective 5-HT1A receptor agonist and 5-HT2 receptor antagonist. This compound demonstrates the ability to modulate receptor-mediated behavioral responses, as evidenced by its induction of a dose-dependent spontaneous tail-flick response in rats, showcasing robust 5-HT1A agonist activity. Additionally, LEK 8804 effectively inhibits 5-HTP-induced head twitch responses in mice, likely through its antagonistic effect on 5-HT2 receptors. This compound is useful for exploring serotonergic mechanisms in behavioral studies and neuropharmacology research.
Chemical Information
| Catalog Num | A29482 |
|---|---|
| M. Wt | 305.37 |
| Formula | C19H19N3O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 153415-44-2 |
| Synonyms | |
| SMILES | [H][C@]1(C2)N(C[C@@H](C=C1C3=CC=CC4=C3C2=CN4)C(NCC#C)=O)C |
Biological Activity
| Description | LEK 8804 is a selective 5-HT1A receptor agonist and 5-HT2 receptor antagonist. This compound demonstrates the ability to modulate receptor-mediated behavioral responses, as evidenced by its induction of a dose-dependent spontaneous tail-flick response in rats, showcasing robust 5-HT1A agonist activity. Additionally, LEK 8804 effectively inhibits 5-HTP-induced head twitch responses in mice, likely through its antagonistic effect on 5-HT2 receptors. This compound is useful for exploring serotonergic mechanisms in behavioral studies and neuropharmacology research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
