Product Data Sheet

5-HT/NA Reuptake inhibitor-1

Catalog No. A29491

main product photo
5-HT/NA Reuptake Inhibitor-1 is a selective dual inhibitor of serotonin (5-HT) and norepinephrine (NA) reuptake, exhibiting IC50 values of 660 nM and 70 nM, respectively. This compound demonstrates favorable in vitro metabolic stability in humans, along with high hERG selectivity and passive membrane permeability. It is primarily utilized in research focused on mood disorders and neuropharmacology, providing valuable insights into the modulation of neurotransmitter systems.
Chemical Information
Catalog NumA29491
M. Wt227.30
FormulaC15H17NO
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.844882-78-6
Synonyms
SMILESCN(C)CC1=C(C=CC=C1)OC2=CC=CC=C2
Biological Activity
Description5-HT/NA Reuptake Inhibitor-1 is a selective dual inhibitor of serotonin (5-HT) and norepinephrine (NA) reuptake, exhibiting IC50 values of 660 nM and 70 nM, respectively. This compound demonstrates favorable in vitro metabolic stability in humans, along with high hERG selectivity and passive membrane permeability. It is primarily utilized in research focused on mood disorders and neuropharmacology, providing valuable insights into the modulation of neurotransmitter systems.
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