Product Data Sheet
PF-4479745
Catalog No. A29523
PF-4479745 is a potent and selective agonist of the 5-HT2C receptor, demonstrating an EC50 of 10 nM and a Ki of 15 nM. This compound has significant biological activity relevant to cardiovascular research, particularly in the study of conditions such as hypertension. Its selectivity for the 5-HT2C receptor makes it an invaluable tool for elucidating the role of serotonin signaling in cardiovascular disease mechanisms.
Chemical Information
| Catalog Num | A29523 |
|---|---|
| M. Wt | 282.38 |
| Formula | C17H22N4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1065110-43-1 |
| Synonyms | |
| SMILES | CNC1=C2C([C@H](CNCC2)C)=NC(CC3=CC=CC=C3)=N1 |
Biological Activity
| Description | PF-4479745 is a potent and selective agonist of the 5-HT2C receptor, demonstrating an EC50 of 10 nM and a Ki of 15 nM. This compound has significant biological activity relevant to cardiovascular research, particularly in the study of conditions such as hypertension. Its selectivity for the 5-HT2C receptor makes it an invaluable tool for elucidating the role of serotonin signaling in cardiovascular disease mechanisms. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
