Product Data Sheet

Donitriptan mesylate

Catalog No. A29538

main product photo
Donitriptan mesylate is a potent agonist of the 5-HT1B and 5-HT1D receptors, demonstrating high efficacy with pKis of 9.4 and 9.3, respectively. This compound is primarily utilized in research focused on migraine treatments and neurological disorders, enabling studies on serotonin receptor signaling pathways. Its strong affinity for 5-HT receptors makes it a valuable tool for exploring the role of serotonin in various biological processes.
Chemical Information
Catalog NumA29538
M. Wt499.58
FormulaC24H29N5O5S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.200615-15-2
SynonymsF-11356 mesylate
SMILESCS(=O)(O)=O.NCCC1=CNC2=C1C=C(OCC(N3CCN(C4=CC=C(C#N)C=C4)CC3)=O)C=C2
Biological Activity
DescriptionDonitriptan mesylate is a potent agonist of the 5-HT1B and 5-HT1D receptors, demonstrating high efficacy with pKis of 9.4 and 9.3, respectively. This compound is primarily utilized in research focused on migraine treatments and neurological disorders, enabling studies on serotonin receptor signaling pathways. Its strong affinity for 5-HT receptors makes it a valuable tool for exploring the role of serotonin in various biological processes.
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SHIPPING AND STORAGE
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