Product Data Sheet

E-6837

Catalog No. A29544

main product photo
E-6837 is an orally active selective ligand for the 5-HT6 receptor, exhibiting partial agonism at the rat 5-HT6 receptor and full agonism at the constitutively active human variant, as evidenced by modulation of the cAMP signaling pathway. This compound has been shown to induce hypophagia, decrease fat mass and body weight, and enhance glycemic control. E-6837 is a valuable tool for research applications related to obesity and metabolic disorders.
Chemical Information
Catalog NumA29544
M. Wt427.95
FormulaC22H22ClN3O2S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.528859-61-2
Synonyms
SMILESO=S(=O)(NC=1C=CC=2NC=C(C2C1)CCN(C)C)C=3C=CC=4C(Cl)=CC=CC4C3
Biological Activity
DescriptionE-6837 is an orally active selective ligand for the 5-HT6 receptor, exhibiting partial agonism at the rat 5-HT6 receptor and full agonism at the constitutively active human variant, as evidenced by modulation of the cAMP signaling pathway. This compound has been shown to induce hypophagia, decrease fat mass and body weight, and enhance glycemic control. E-6837 is a valuable tool for research applications related to obesity and metabolic disorders.
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