Product Data Sheet
5-HT7R antagonist 3
Catalog No. A29551
5-HT7R Antagonist 3 is a selective antagonist of the 5-HT7 receptor, exhibiting a Ki value of 8 nM, which illustrates its high affinity for the target. It shows lower affinity for other receptors, such as D2 (Ki: 511 nM), 5-HT1A (Ki: 8930 nM), and 5-HT2A (Ki: 5786 nM). This compound demonstrates significant antidepressant and anxiolytic effects in murine models, making it a valuable tool for research in mood disorders and anxiety-related conditions.
Chemical Information
| Catalog Num | A29551 |
|---|---|
| M. Wt | 516.61 |
| Formula | C30H33FN4O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1887043-58-4 |
| Synonyms | |
| SMILES | O=C1N(C[C@H](O)CN2CCN(C(C3=CC=CC=C3)C4=CC=CC=C4)CC2)C([C@](C)(C5=CC=C(F)C=C5)N1)=O |
Biological Activity
| Description | 5-HT7R Antagonist 3 is a selective antagonist of the 5-HT7 receptor, exhibiting a Ki value of 8 nM, which illustrates its high affinity for the target. It shows lower affinity for other receptors, such as D2 (Ki: 511 nM), 5-HT1A (Ki: 8930 nM), and 5-HT2A (Ki: 5786 nM). This compound demonstrates significant antidepressant and anxiolytic effects in murine models, making it a valuable tool for research in mood disorders and anxiety-related conditions. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
