Product Data Sheet
LY-272015
Catalog No. A29558
LY-272015 is a selective antagonist of the 5-HT2B receptor, demonstrating efficacy in modulating signaling pathways related to serotonin activity. It effectively inhibits the phosphorylation of ERK2 induced by serotonin or BW723C86, making it a valuable tool for studying serotonin receptor functions. Additionally, LY-272015 exhibits antihypertensive properties in animal models, specifically in Deoxycorticosterone Acetate (DOCA)-salt-hypertensive rats, supporting its use in cardiovascular research.
Chemical Information
| Catalog Num | A29558 |
|---|---|
| M. Wt | 336.43 |
| Formula | C21H24N2O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 159730-07-1 |
| Synonyms | |
| SMILES | CC1=CC2=C(NC3=C2CCNC3CC4=CC=C(OC)C(OC)=C4)C=C1 |
Biological Activity
| Description | LY-272015 is a selective antagonist of the 5-HT2B receptor, demonstrating efficacy in modulating signaling pathways related to serotonin activity. It effectively inhibits the phosphorylation of ERK2 induced by serotonin or BW723C86, making it a valuable tool for studying serotonin receptor functions. Additionally, LY-272015 exhibits antihypertensive properties in animal models, specifically in Deoxycorticosterone Acetate (DOCA)-salt-hypertensive rats, supporting its use in cardiovascular research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
