Product Data Sheet
PRX-03140
Catalog No. A29559
PRX-03140 is a selective 5-HT4 receptor agonist that effectively crosses the blood-brain barrier, exhibiting a Ki value of 110 nM against the rat brain 5-HT4 receptor. This compound enhances cortical levels of acetylcholine and histamine, making it a valuable tool for investigating cognitive function. PRX-03140 is particularly relevant for research applications related to Alzheimer’s disease, where modulation of neurotransmitter systems is critical.
Chemical Information
| Catalog Num | A29559 |
|---|---|
| M. Wt | 377.50 |
| Formula | C19H27N3O3S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 869493-21-0 |
| Synonyms | VRX-03011 free base |
| SMILES | O=C(NCCCN1CCCCC1)C=2C(=O)N(C=3SC=CC3C2O)C(C)C |
Biological Activity
| Description | PRX-03140 is a selective 5-HT4 receptor agonist that effectively crosses the blood-brain barrier, exhibiting a Ki value of 110 nM against the rat brain 5-HT4 receptor. This compound enhances cortical levels of acetylcholine and histamine, making it a valuable tool for investigating cognitive function. PRX-03140 is particularly relevant for research applications related to Alzheimer’s disease, where modulation of neurotransmitter systems is critical. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
