Product Data Sheet
Donitriptan hydrochloride
Catalog No. A29560
Donitriptan hydrochloride is a potent agonist of the 5-HT1B and 5-HT1D receptors, exhibiting high efficacy with pKis of 9.4 and 9.3, respectively. This compound is primarily utilized in research focused on migraine treatments and the modulation of serotonin pathways. Its strong receptor activity makes it a valuable tool for studying the pharmacological effects of serotonin receptor signaling in various biological contexts.
Chemical Information
| Catalog Num | A29560 |
|---|---|
| M. Wt | 439.94 |
| Formula | C23H26ClN5O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 170911-68-9 |
| Synonyms | F-11356 |
| SMILES | N#CC1=CC=C(N2CCN(C(COC3=CC4=C(NC=C4CCN)C=C3)=O)CC2)C=C1.[H]Cl |
Biological Activity
| Description | Donitriptan hydrochloride is a potent agonist of the 5-HT1B and 5-HT1D receptors, exhibiting high efficacy with pKis of 9.4 and 9.3, respectively. This compound is primarily utilized in research focused on migraine treatments and the modulation of serotonin pathways. Its strong receptor activity makes it a valuable tool for studying the pharmacological effects of serotonin receptor signaling in various biological contexts. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
