Product Data Sheet
SB 242084 monohydrochloride
Catalog No. A29570
SB 242084 monohydrochloride is a selective and high-affinity antagonist of the 5-HT2C receptor with a pKi value of 9.0. This compound effectively enhances the basal activity of dopaminergic neurons in the ventral tegmental area, stimulating dopamine release in the vomeronasal nucleus. Additionally, SB 242084 promotes mitochondrial gene expression and oxidative metabolism through 5-HT2A receptor interactions. Its potential applications in research include the investigation of negative symptoms associated with anxiety, depression, and schizophrenia, as well as the study of acute organ damage.
Chemical Information
| Catalog Num | A29570 |
|---|---|
| M. Wt | 431.32 |
| Formula | C21H20Cl2N4O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1260505-34-7 |
| Synonyms | |
| SMILES | O=C(N1CCC2=C1C=C(Cl)C(C)=C2)NC3=CC=C(OC4=CC=CN=C4C)N=C3.[H]Cl |
Biological Activity
| Description | SB 242084 monohydrochloride is a selective and high-affinity antagonist of the 5-HT2C receptor with a pKi value of 9.0. This compound effectively enhances the basal activity of dopaminergic neurons in the ventral tegmental area, stimulating dopamine release in the vomeronasal nucleus. Additionally, SB 242084 promotes mitochondrial gene expression and oxidative metabolism through 5-HT2A receptor interactions. Its potential applications in research include the investigation of negative symptoms associated with anxiety, depression, and schizophrenia, as well as the study of acute organ damage. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
