Product Data Sheet
Opiranserin
Catalog No. A29584
Opiranserin is a dual antagonist of the glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A), exhibiting IC50 values of 0.86 μM and 1.3 μM, respectively. Additionally, it demonstrates antagonistic activity on the recombinant P2X3 receptor with an IC50 of 0.87 μM. This compound is being developed as an injectable analgesic for the management of postoperative pain, highlighting its potential utility in pain research and pharmacological studies.
Chemical Information
| Catalog Num | A29584 |
|---|---|
| M. Wt | 394.51 |
| Formula | C21H34N2O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1441000-45-8 |
| Synonyms | VVZ-149 |
| SMILES | O=C(C1=CC(OC)=C(OCCCC)C(OC)=C1)NCC2(CCOCC2)N(C)C |
Biological Activity
| Description | Opiranserin is a dual antagonist of the glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A), exhibiting IC50 values of 0.86 μM and 1.3 μM, respectively. Additionally, it demonstrates antagonistic activity on the recombinant P2X3 receptor with an IC50 of 0.87 μM. This compound is being developed as an injectable analgesic for the management of postoperative pain, highlighting its potential utility in pain research and pharmacological studies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
