Product Data Sheet

E-55888

Catalog No. A29606

main product photo
E-55888 is a selective and potent agonist of the 5-HT7 and 5-HT1A receptors, exhibiting Ki values of 2.5 nM and 700 nM, respectively. This compound demonstrates significant analgesic and antinociceptive properties, effectively reducing the nociceptive response in capsaicin-sensitized mice. E-55888 serves as a valuable tool for researchers investigating pain mechanisms and therapeutic approaches to pain management.
Chemical Information
Catalog NumA29606
M. Wt257.37
FormulaC16H23N3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1034142-33-0
Synonyms
SMILESCC1=C(C2=CC(CCN(C)C)=CC=C2)C(C)=NN1C
Biological Activity
DescriptionE-55888 is a selective and potent agonist of the 5-HT7 and 5-HT1A receptors, exhibiting Ki values of 2.5 nM and 700 nM, respectively. This compound demonstrates significant analgesic and antinociceptive properties, effectively reducing the nociceptive response in capsaicin-sensitized mice. E-55888 serves as a valuable tool for researchers investigating pain mechanisms and therapeutic approaches to pain management.
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