Product Data Sheet
EGIS-7625
Catalog No. A29617
EGIS-7625 is a selective competitive inhibitor of the 5-HT2B receptor, exhibiting pKi values of 9.0 for 5-HT2B, and 6.2 and 7.7 for 5-HT2A and 5-HT2C, respectively. This compound has been shown to partially counteract m-chlorophenylpiperazine-induced hypomotility and hypophagia. EGIS-7625 is a valuable tool for investigating the role of 5-HT2B in various physiological and pathological processes, making it suitable for research in neuropharmacology and behavioral studies.
Chemical Information
| Catalog Num | A29617 |
|---|---|
| M. Wt | 399.31 |
| Formula | C18H24Cl2N4O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 755040-97-2 |
| Synonyms | |
| SMILES | NC1=CC(N2CCN(CC3=CC=CC=C3)CC2)=C([N+]([O-])=O)C=C1C.Cl.Cl |
Biological Activity
| Description | EGIS-7625 is a selective competitive inhibitor of the 5-HT2B receptor, exhibiting pKi values of 9.0 for 5-HT2B, and 6.2 and 7.7 for 5-HT2A and 5-HT2C, respectively. This compound has been shown to partially counteract m-chlorophenylpiperazine-induced hypomotility and hypophagia. EGIS-7625 is a valuable tool for investigating the role of 5-HT2B in various physiological and pathological processes, making it suitable for research in neuropharmacology and behavioral studies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
