LY302148
Catalog No. A29631

LY302148 is a partial agonist of the 5-HT1F receptor, demonstrating significant interaction with this target. In the [35S]GTPγS binding assay for human 5-HT1F receptors, it exhibits a potent EC50 value of 5.23 nM. This compound is of interest for research applications related to migraine pathophysiology and the potential development of therapeutic strategies.
Chemical Information
| Catalog Num | A29631 |
|---|---|
| M. Wt | 326.41 |
| Formula | C19H23FN4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 182564-47-2 |
| Synonyms | |
| SMILES | CN1N=CC(CCN2CCC(C3=CNC4=C3C=C(F)C=C4)CC2)=C1 |
Biological Activity
| Description | LY302148 is a partial agonist of the 5-HT1F receptor, demonstrating significant interaction with this target. In the [35S]GTPγS binding assay for human 5-HT1F receptors, it exhibits a potent EC50 value of 5.23 nM. This compound is of interest for research applications related to migraine pathophysiology and the potential development of therapeutic strategies. |
|---|
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
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Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


