Product Data Sheet

LY302148

Catalog No. A29631

main product photo
LY302148 is a partial agonist of the 5-HT1F receptor, demonstrating significant interaction with this target. In the [35S]GTPγS binding assay for human 5-HT1F receptors, it exhibits a potent EC50 value of 5.23 nM. This compound is of interest for research applications related to migraine pathophysiology and the potential development of therapeutic strategies.
Chemical Information
Catalog NumA29631
M. Wt326.41
FormulaC19H23FN4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.182564-47-2
Synonyms
SMILESCN1N=CC(CCN2CCC(C3=CNC4=C3C=C(F)C=C4)CC2)=C1
Biological Activity
DescriptionLY302148 is a partial agonist of the 5-HT1F receptor, demonstrating significant interaction with this target. In the [35S]GTPγS binding assay for human 5-HT1F receptors, it exhibits a potent EC50 value of 5.23 nM. This compound is of interest for research applications related to migraine pathophysiology and the potential development of therapeutic strategies.
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