Product Data Sheet

Lintopride hydrochloride

Catalog No. A29637

main product photo
Lintopride hydrochloride is a benzamide derivative that acts as a potent antagonist of the 5HT-4 receptor and exhibits moderate antagonistic effects on the 5HT-3 receptor. This compound enhances gastric emptying, stimulates antral and duodenal motility, and accelerates intestinal transit in preclinical models. Additionally, Lintopride hydrochloride significantly elevates the basal tone of the lower esophageal sphincter, making it valuable for research on gastrointestinal motility and related disorders.
Chemical Information
Catalog NumA29637
M. Wt347.24
FormulaC14H20Cl2N4O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.268548-31-8
Synonyms
SMILESO=C(NCC1=NCCN1CC)C2=CC(Cl)=C(N)C=C2OC.[H]Cl
Biological Activity
DescriptionLintopride hydrochloride is a benzamide derivative that acts as a potent antagonist of the 5HT-4 receptor and exhibits moderate antagonistic effects on the 5HT-3 receptor. This compound enhances gastric emptying, stimulates antral and duodenal motility, and accelerates intestinal transit in preclinical models. Additionally, Lintopride hydrochloride significantly elevates the basal tone of the lower esophageal sphincter, making it valuable for research on gastrointestinal motility and related disorders.
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