Product Data Sheet

SB357134

Catalog No. A29650

main product photo
SB357134 is a potent and selective antagonist of the 5-HT6 receptor, demonstrating significant brain penetration and oral bioavailability. This compound has been shown to enhance memory and learning capabilities while increasing seizure thresholds in rodent models. It is valuable for research applications focused on neuropharmacology, cognitive function, and the modulation of serotonergic signaling pathways.
Chemical Information
Catalog NumA29650
M. Wt523.21
FormulaC17H18Br2FN3O3S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.219963-52-7
Synonyms
SMILESO=S(C1=CC=C(C(N2CCNCC2)=C1)OC)(NC3=CC(Br)=CC(F)=C3Br)=O
Biological Activity
DescriptionSB357134 is a potent and selective antagonist of the 5-HT6 receptor, demonstrating significant brain penetration and oral bioavailability. This compound has been shown to enhance memory and learning capabilities while increasing seizure thresholds in rodent models. It is valuable for research applications focused on neuropharmacology, cognitive function, and the modulation of serotonergic signaling pathways.
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SHIPPING AND STORAGE
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