Product Data Sheet
Methiothepin maleate
Catalog No. A29667
Methiothepin maleate is a potent and non-selective antagonist of the 5-HT2 receptor family, demonstrating affinity with pKis of 8.50 for 5-HT2A, 8.68 for 5-HT2B, and 8.35 for 5-HT2C. This compound effectively inhibits various serotonin receptor subtypes, including 5-HT1A through 5-HT7, making it a valuable tool for studying serotonin signaling pathways. Methiothepin maleate is commonly used in neuropharmacology research to investigate the role of serotonin in mood regulation, psychosis, and related disorders.
Chemical Information
| Catalog Num | A29667 |
|---|---|
| M. Wt | 472.62 |
| Formula | C24H28N2O4S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 19728-88-2 |
| Synonyms | Metitepine maleate; Ro-8-6837 maleate |
| SMILES | CN1CCN(C2CC3=CC=CC=C3SC4=CC=C(SC)C=C24)CC1.OC(/C=C\C(O)=O)=O |
Biological Activity
| Description | Methiothepin maleate is a potent and non-selective antagonist of the 5-HT2 receptor family, demonstrating affinity with pKis of 8.50 for 5-HT2A, 8.68 for 5-HT2B, and 8.35 for 5-HT2C. This compound effectively inhibits various serotonin receptor subtypes, including 5-HT1A through 5-HT7, making it a valuable tool for studying serotonin signaling pathways. Methiothepin maleate is commonly used in neuropharmacology research to investigate the role of serotonin in mood regulation, psychosis, and related disorders. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
