Product Data Sheet
S-14489
Catalog No. A29673
S-14489 is a selective antagonist of the postsynaptic 5-HT1A receptor, exhibiting a high affinity with a pKi of 9.2. This compound can function as an agonist at 5-HT1A autoreceptors and effectively inhibit the accumulation of 5-hydroxytryptophan in the striatum. S-14489 is primarily employed in neurological research, particularly for studying disorders related to serotonin signaling.
Chemical Information
| Catalog Num | A29673 |
|---|---|
| M. Wt | 350.45 |
| Formula | C22H26N2O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 153607-44-4 |
| Synonyms | |
| SMILES | C12=CC=CC(N3CCN(CCC4C5=C(C4)C=CC=C5)CC3)=C1OCCO2 |
Biological Activity
| Description | S-14489 is a selective antagonist of the postsynaptic 5-HT1A receptor, exhibiting a high affinity with a pKi of 9.2. This compound can function as an agonist at 5-HT1A autoreceptors and effectively inhibit the accumulation of 5-hydroxytryptophan in the striatum. S-14489 is primarily employed in neurological research, particularly for studying disorders related to serotonin signaling. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
