Product Data Sheet
LP 12 hydrochloride
Catalog No. A29674
LP 12 hydrochloride is a potent and selective agonist of the 5-HT7 receptor, exhibiting a Ki value of 0.13 nM. This compound demonstrates significant selectivity for the 5-HT7 receptor compared to D2, 5-HT1A, and 5-HT2A receptors, with Ki values of 224 nM, 60.9 nM, and >1000 nM, respectively. LP 12 hydrochloride is valuable for research applications focusing on serotonin receptor signaling and its implications in neuropharmacology.
Chemical Information
| Catalog Num | A29674 |
|---|---|
| M. Wt | 518.13 |
| Formula | C32H40ClN3O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1185136-22-4 |
| Synonyms | |
| SMILES | O=C(NC1CCCC2=C1C=CC=C2)CCCCCN3CCN(C4=CC=CC=C4C5=CC=CC=C5)CC3.[H]Cl |
Biological Activity
| Description | LP 12 hydrochloride is a potent and selective agonist of the 5-HT7 receptor, exhibiting a Ki value of 0.13 nM. This compound demonstrates significant selectivity for the 5-HT7 receptor compared to D2, 5-HT1A, and 5-HT2A receptors, with Ki values of 224 nM, 60.9 nM, and >1000 nM, respectively. LP 12 hydrochloride is valuable for research applications focusing on serotonin receptor signaling and its implications in neuropharmacology. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
