Product Data Sheet
WAY-181187 hydrochloride
Catalog No. A29677
WAY-181187 hydrochloride is a potent and selective full agonist of the 5-HT6 receptor, exhibiting a Ki of 2.2 nM and an EC50 of 6.6 nM. This compound activates 5-HT6 receptor-dependent signaling pathways, including cAMP, Fyn, and ERK1/2 kinase, making it a valuable tool for research into neuropharmacology and the modulation of serotonergic pathways. Its selective action supports investigations into potential therapeutic applications for cognitive disorders and other conditions influenced by serotonin signaling.
Chemical Information
| Catalog Num | A29677 |
|---|---|
| M. Wt | 417.33 |
| Formula | C15H14Cl2N4O2S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 554403-08-6 |
| Synonyms | SAX-187 hydrochloride |
| SMILES | NCCC1=CN(S(=O)(C2=C(Cl)N=C3SC=CN32)=O)C4=C1C=CC=C4.[H]Cl |
Biological Activity
| Description | WAY-181187 hydrochloride is a potent and selective full agonist of the 5-HT6 receptor, exhibiting a Ki of 2.2 nM and an EC50 of 6.6 nM. This compound activates 5-HT6 receptor-dependent signaling pathways, including cAMP, Fyn, and ERK1/2 kinase, making it a valuable tool for research into neuropharmacology and the modulation of serotonergic pathways. Its selective action supports investigations into potential therapeutic applications for cognitive disorders and other conditions influenced by serotonin signaling. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
