Product Data Sheet

Ondansetron-13C,d3

Catalog No. A29707

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Ondansetron-13C,d3 is a stable isotope-labeled variant of Ondansetron, a selective 5-HT3 receptor antagonist with an IC50 of 103 pM. This compound inhibits nausea and vomiting by blocking 5-HT receptors in both peripheral and central nervous systems. It is particularly valuable in research applications involving the effects of chemotherapy and radiotherapy on antiemetic responses. Used in pharmacokinetic studies and metabolic research, Ondansetron-13C,d3 aids in understanding the drug's behavior and efficacy in clinical settings.
Chemical Information
Catalog NumA29707
M. Wt297.37
FormulaC1713CH16D3N3O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2699607-85-5
SynonymsGR 38032-13C,d3; SN 307-13C,d3
SMILESO=C1C(CN2C=CN=C2C)CCC(N3[13C]([2H])([2H])[2H])=C1C4=C3C=CC=C4
Biological Activity
DescriptionOndansetron-13C,d3 is a stable isotope-labeled variant of Ondansetron, a selective 5-HT3 receptor antagonist with an IC50 of 103 pM. This compound inhibits nausea and vomiting by blocking 5-HT receptors in both peripheral and central nervous systems. It is particularly valuable in research applications involving the effects of chemotherapy and radiotherapy on antiemetic responses. Used in pharmacokinetic studies and metabolic research, Ondansetron-13C,d3 aids in understanding the drug's behavior and efficacy in clinical settings.
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SHIPPING AND STORAGE
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