Product Data Sheet
Ro 63-0563
Catalog No. A29727
Ro 63-0563 is a potent and selective antagonist of the 5-HT6 receptor, exhibiting competitive inhibition with pKi values of 7.83 and 7.91 for rat and human 5-HT6 receptors, respectively. This compound demonstrates minimal off-target effects, displaying no affinity for other receptors. It is relevant in exploring the role of 5-HT6 in neurological disorders and may be useful in research focused on neuropharmacology and cognitive function.
Chemical Information
| Catalog Num | A29727 |
|---|---|
| M. Wt | 307.37 |
| Formula | C13H17N5O2S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 202466-77-1 |
| Synonyms | |
| SMILES | O=S(C1=CC=C(C=C1)N)(NC2=CC(NC)=NC(NC)=C2)=O |
Biological Activity
| Description | Ro 63-0563 is a potent and selective antagonist of the 5-HT6 receptor, exhibiting competitive inhibition with pKi values of 7.83 and 7.91 for rat and human 5-HT6 receptors, respectively. This compound demonstrates minimal off-target effects, displaying no affinity for other receptors. It is relevant in exploring the role of 5-HT6 in neurological disorders and may be useful in research focused on neuropharmacology and cognitive function. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
