Product Data Sheet

CYD-1-79

Catalog No. A29735

main product photo
CYD-1-79 is a selective positive allosteric modulator of the 5-HT2C receptor. This compound enhances 5-HT-induced intracellular calcium release through a distinct allosteric site, demonstrating significant inhibition at dopamine D3 receptors, DAT, and α2A/α2B adrenergic receptors. CYD-1-79 has been shown to modulate spontaneous ambulation in rodents and can synergize with low doses of 5-HT2C receptor agonists. Additionally, it reduces relapse vulnerability in models of psychoactive substance self-administration, highlighting its potential applications in neurological disease research.
Chemical Information
Catalog NumA29735
M. Wt356.54
FormulaC20H40N2O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2220235-94-7
Synonyms
SMILESO=C([C@H]1NCC[C@@H](CCCCCCCCCCC)C1)NCC(O)CO
Biological Activity
DescriptionCYD-1-79 is a selective positive allosteric modulator of the 5-HT2C receptor. This compound enhances 5-HT-induced intracellular calcium release through a distinct allosteric site, demonstrating significant inhibition at dopamine D3 receptors, DAT, and α2A/α2B adrenergic receptors. CYD-1-79 has been shown to modulate spontaneous ambulation in rodents and can synergize with low doses of 5-HT2C receptor agonists. Additionally, it reduces relapse vulnerability in models of psychoactive substance self-administration, highlighting its potential applications in neurological disease research.
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