Product Data Sheet
VU0530244
Catalog No. A29741
VU0530244 is a highly potent antagonist of the serotonin 5-HT2B receptor, exhibiting an IC50 of 17.3 nM. Due to its predicted properties, VU0530244 is expected to have minimal brain penetration in human subjects and is likely a substrate for P-glycoprotein-mediated efflux. This compound is useful for research applications focused on serotonin receptor signaling and its implications in various physiological and pathological processes.
Chemical Information
| Catalog Num | A29741 |
|---|---|
| M. Wt | 389.43 |
| Formula | C22H20FN5O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1396886-30-8 |
| Synonyms | |
| SMILES | O=C(N1CC(C1)C2=NC3=C(N2)C=C(C)C=C3)C4=CC(C5=CC=C(F)C=C5)=NN4C |
Biological Activity
| Description | VU0530244 is a highly potent antagonist of the serotonin 5-HT2B receptor, exhibiting an IC50 of 17.3 nM. Due to its predicted properties, VU0530244 is expected to have minimal brain penetration in human subjects and is likely a substrate for P-glycoprotein-mediated efflux. This compound is useful for research applications focused on serotonin receptor signaling and its implications in various physiological and pathological processes. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
