Product Data Sheet

WAY-181187 oxalate

Catalog No. A29747

main product photo
WAY-181187 oxalate is a selective full agonist of the 5-HT6 receptor, exhibiting a binding affinity with a Ki of 2.2 nM and an effective concentration for half-maximal activation (EC50) of 6.6 nM. This compound engages 5-HT6 receptor-mediated signaling pathways, influencing cAMP, Fyn, and ERK1/2 kinase activity. It serves as a valuable tool for research into neuropharmacology and potential therapeutic applications targeting cognitive disorders.
Chemical Information
Catalog NumA29747
M. Wt470.91
FormulaC17H15ClN4O6S2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1883548-85-3
SynonymsSAX-187 oxalate
SMILESOC(=O)C(O)=O.NCCc1cn(c2ccccc12)S(=O)(=O)c1c(Cl)nc2sccn12
Biological Activity
DescriptionWAY-181187 oxalate is a selective full agonist of the 5-HT6 receptor, exhibiting a binding affinity with a Ki of 2.2 nM and an effective concentration for half-maximal activation (EC50) of 6.6 nM. This compound engages 5-HT6 receptor-mediated signaling pathways, influencing cAMP, Fyn, and ERK1/2 kinase activity. It serves as a valuable tool for research into neuropharmacology and potential therapeutic applications targeting cognitive disorders.
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SHIPPING AND STORAGE
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