Product Data Sheet
GR125487
Catalog No. A29765
GR125487 is a highly selective antagonist of the 5-HT4 receptor, exhibiting a Kd value of 0.1 nM. It demonstrates minimal binding affinity for 5-HT3 receptors (Kd > 1 μM), ensuring specificity in its action. GR125487 effectively inhibits the memory-enhancing effects of BIMU1 without significantly affecting baseline social memory. This compound is valuable for investigating mechanisms underlying social olfactory memory and related cognitive processes.
Chemical Information
| Catalog Num | A29765 |
|---|---|
| M. Wt | 427.49 |
| Formula | C19H26FN3O5S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 144625-67-2 |
| Synonyms | |
| SMILES | O=C(OCC1CCN(CCNS(=O)(=O)C)CC1)C2=C(OC)NC=3C=CC(F)=CC32 |
Biological Activity
| Description | GR125487 is a highly selective antagonist of the 5-HT4 receptor, exhibiting a Kd value of 0.1 nM. It demonstrates minimal binding affinity for 5-HT3 receptors (Kd > 1 μM), ensuring specificity in its action. GR125487 effectively inhibits the memory-enhancing effects of BIMU1 without significantly affecting baseline social memory. This compound is valuable for investigating mechanisms underlying social olfactory memory and related cognitive processes. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
