Product Data Sheet
NAS-181
Catalog No. A29781
NAS-181 is a potent and selective antagonist of the rat 5-hydroxytryptamine 1B (r5-HT1B) receptor, exhibiting an Ki value of 47 nM. This compound has demonstrated an ability to increase 5-hydroxytryptophan (5-HTP) accumulation in various rat brain regions. Its significant biological activity makes NAS-181 a valuable tool for investigating serotonergic signaling pathways and their implications in neuropharmacological research.
Chemical Information
| Catalog Num | A29781 |
|---|---|
| M. Wt | 442.53 |
| Formula | C20H30N2O7S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 205242-62-2 |
| Synonyms | |
| SMILES | CS(=O)(O)=O.[C@H]1(COC2=C3C(C=C(CN4CCOCC4)CO3)=CC=C2)CNCCO1 |
Biological Activity
| Description | NAS-181 is a potent and selective antagonist of the rat 5-hydroxytryptamine 1B (r5-HT1B) receptor, exhibiting an Ki value of 47 nM. This compound has demonstrated an ability to increase 5-hydroxytryptophan (5-HTP) accumulation in various rat brain regions. Its significant biological activity makes NAS-181 a valuable tool for investigating serotonergic signaling pathways and their implications in neuropharmacological research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
