Product Data Sheet
SB-221284
Catalog No. A29789
SB-221284 is a selective antagonist of the 5-HT2C and 5-HT2B receptors, exhibiting pKi values of 6.4, 7.9, and 8.6 for the 5-HT2A, 5-HT2B, and 5-HT2C receptors, respectively. This compound is valuable in studying the role of serotonergic signaling in neurological diseases and may contribute to the development of therapeutic strategies targeting these receptors. Its specificity makes it a useful tool for researching the physiological and pathological functions associated with serotonin receptors.
Chemical Information
| Catalog Num | A29789 |
|---|---|
| M. Wt | 353.36 |
| Formula | C16H14F3N3OS |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 196965-14-7 |
| Synonyms | |
| SMILES | O=C(N1CCC2=C1C=C(C(F)(F)F)C(SC)=C2)NC3=CC=CN=C3 |
Biological Activity
| Description | SB-221284 is a selective antagonist of the 5-HT2C and 5-HT2B receptors, exhibiting pKi values of 6.4, 7.9, and 8.6 for the 5-HT2A, 5-HT2B, and 5-HT2C receptors, respectively. This compound is valuable in studying the role of serotonergic signaling in neurological diseases and may contribute to the development of therapeutic strategies targeting these receptors. Its specificity makes it a useful tool for researching the physiological and pathological functions associated with serotonin receptors. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
