Product Data Sheet
GTS-21 (DMBX-A)
Catalog No. A29791
GTS-21 is a selective agonist of the alpha7 nicotinic acetylcholine receptor (α7-nAChR), known for its anti-inflammatory and cognitive-enhancing properties. Additionally, GTS-21 exhibits antagonistic activity at the α4β2 receptor (Ki=20 nM) and the 5-HT3A receptor (IC50=3.1 μM). This compound is utilized in research related to age-associated memory impairment (AAMI) and Alzheimer's disease, making it a valuable tool for investigating cognitive dysfunction and neuroinflammatory processes.
Chemical Information
| Catalog Num | A29791 |
|---|---|
| M. Wt | 308.37 |
| Formula | C19H20N2O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 148372-04-7 |
| Synonyms | |
| SMILES | COC(C=C(C=C1)OC)=C1/C=C2C(C3=CN=CC=C3)=NCCC/2 |
Biological Activity
| Description | GTS-21 is a selective agonist of the alpha7 nicotinic acetylcholine receptor (α7-nAChR), known for its anti-inflammatory and cognitive-enhancing properties. Additionally, GTS-21 exhibits antagonistic activity at the α4β2 receptor (Ki=20 nM) and the 5-HT3A receptor (IC50=3.1 μM). This compound is utilized in research related to age-associated memory impairment (AAMI) and Alzheimer's disease, making it a valuable tool for investigating cognitive dysfunction and neuroinflammatory processes. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
