Product Data Sheet
Isamoltane hemifumarate
Catalog No. A29796
Isamoltane hemifumarate is a selective antagonist of the 5-HT1B receptor, exhibiting an IC50 value of 39 nM for the inhibition of [125I]ICYP binding to 5-HT1B recognition sites in rat brain membranes. Additionally, it functions as a β-adrenoceptor ligand with an IC50 of 8.4 nM. Due to its mechanism of action, Isamoltane hemifumarate demonstrates significant anxiolytic activity, making it a valuable tool for studies in anxiety disorders and related neuropharmacological research.
Chemical Information
| Catalog Num | A29796 |
|---|---|
| M. Wt | 332.40 |
| Formula | C16H22N2O2.1/2C4H4O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 874882-92-5 |
| Synonyms | (±)-Isamoltane hemifumarate |
| SMILES | OC(COC1=CC=CC=C1N2C=CC=C2)CNC(C)C.O=C(O)/C=C/C(O)=O.[1/2] |
Biological Activity
| Description | Isamoltane hemifumarate is a selective antagonist of the 5-HT1B receptor, exhibiting an IC50 value of 39 nM for the inhibition of [125I]ICYP binding to 5-HT1B recognition sites in rat brain membranes. Additionally, it functions as a β-adrenoceptor ligand with an IC50 of 8.4 nM. Due to its mechanism of action, Isamoltane hemifumarate demonstrates significant anxiolytic activity, making it a valuable tool for studies in anxiety disorders and related neuropharmacological research. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
