Product Data Sheet
Lurasidone-d8
Catalog No. A29800
Lurasidone-d8 is a deuterium-labeled derivative of Lurasidone, which acts as an antagonist of dopamine D2 and 5-HT7 receptors, exhibiting IC50 values of 1.68 nM and 0.495 nM, respectively. Additionally, Lurasidone functions as a partial agonist at the 5-HT1A receptor with an IC50 of 6.75 nM. This stable isotope is utilized in biological research for tracing studies, pharmacokinetic profiling, and investigating receptor interactions.
Chemical Information
| Catalog Num | A29800 |
|---|---|
| M. Wt | 500.73 |
| Formula | C28H28D8N4O2S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1132654-54-6 |
| Synonyms | SM-13496-d8 |
| SMILES | O=C1[C@@]2([H])[C@](C(N1C[C@H]3[C@@H](CCCC3)CN4C([2H])([2H])C([2H])([2H])N(C5=NSC6=CC=CC=C56)C([2H])([2H])C4([2H])[2H])=O)([H])[C@H]7C[C@@H]2CC7 |
Biological Activity
| Description | Lurasidone-d8 is a deuterium-labeled derivative of Lurasidone, which acts as an antagonist of dopamine D2 and 5-HT7 receptors, exhibiting IC50 values of 1.68 nM and 0.495 nM, respectively. Additionally, Lurasidone functions as a partial agonist at the 5-HT1A receptor with an IC50 of 6.75 nM. This stable isotope is utilized in biological research for tracing studies, pharmacokinetic profiling, and investigating receptor interactions. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
