Product Data Sheet
Lerimazoline
Catalog No. A29801
Lerimazoline is a selective agonist of the 5-HT1D receptor, exhibiting Ki values of 72 nM and 3480 nM for h5-HT1D and h5-HT1B receptors, respectively. This compound effectively inhibits Forskolin-induced cAMP production and stimulates contractions in rabbit saphenous vein preparations. Lerimazoline's pharmacological profile makes it a valuable tool for research into migraine pathophysiology and related therapeutic strategies.
Chemical Information
| Catalog Num | A29801 |
|---|---|
| M. Wt | 202.30 |
| Formula | C13H18N2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 54765-26-3 |
| Synonyms | |
| SMILES | CC1=C(CC2=NCCN2)C(C)=CC(C)=C1 |
Biological Activity
| Description | Lerimazoline is a selective agonist of the 5-HT1D receptor, exhibiting Ki values of 72 nM and 3480 nM for h5-HT1D and h5-HT1B receptors, respectively. This compound effectively inhibits Forskolin-induced cAMP production and stimulates contractions in rabbit saphenous vein preparations. Lerimazoline's pharmacological profile makes it a valuable tool for research into migraine pathophysiology and related therapeutic strategies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
