Product Data Sheet
MW073
Catalog No. A29830
MW073 is a potent and selective antagonist of the 5-HT2B receptor, exhibiting an IC50 of 70 nM. This compound inhibits receptor activity and β-arrestin-1 recruitment in a concentration-dependent manner. MW073 has demonstrated the ability to improve synaptic plasticity and alleviate behavioral deficits, including aggression, in mouse models of Alzheimer’s disease. It is suitable for research applications focused on Alzheimer’s disease and related neurological conditions.
Chemical Information
| Catalog Num | A29830 |
|---|---|
| M. Wt | 361.48 |
| Formula | C22H27N5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3048608-87-0 |
| Synonyms | |
| SMILES | CN1CCN(CC1)CCNC2=NN=C(C=C2C)C3=CC=C4C=CC=CC4=C3 |
Biological Activity
| Description | MW073 is a potent and selective antagonist of the 5-HT2B receptor, exhibiting an IC50 of 70 nM. This compound inhibits receptor activity and β-arrestin-1 recruitment in a concentration-dependent manner. MW073 has demonstrated the ability to improve synaptic plasticity and alleviate behavioral deficits, including aggression, in mouse models of Alzheimer’s disease. It is suitable for research applications focused on Alzheimer’s disease and related neurological conditions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
