Product Data Sheet
AGH-107
Catalog No. A29843
AGH-107 is a highly selective agonist of the 5-HT7 receptor, demonstrating a Ki of 6 nM and an EC50 of 19 nM. It exhibits considerable brain penetration, along with high selectivity for the 5-HT7 receptor over related CNS targets. AGH-107 has also been shown to possess high metabolic stability and low toxicity in HEK-293 and HepG2 cell cultures, making it a valuable tool for studying serotonergic signaling and its implications in neuropsychiatric disorders.
Chemical Information
| Catalog Num | A29843 |
|---|---|
| M. Wt | 337.16 |
| Formula | C13H12IN3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2172907-10-5 |
| Synonyms | |
| SMILES | IC1=CC=C2NC=C(C3=CN=CN3CC)C2=C1 |
Biological Activity
| Description | AGH-107 is a highly selective agonist of the 5-HT7 receptor, demonstrating a Ki of 6 nM and an EC50 of 19 nM. It exhibits considerable brain penetration, along with high selectivity for the 5-HT7 receptor over related CNS targets. AGH-107 has also been shown to possess high metabolic stability and low toxicity in HEK-293 and HepG2 cell cultures, making it a valuable tool for studying serotonergic signaling and its implications in neuropsychiatric disorders. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
