Product Data Sheet
Pellotine
Catalog No. A29845
Pellotine is an alkaloid that acts as an inverse agonist targeting the 5-HT7 receptor, exhibiting an EC50 of 291 nM. This compound also demonstrates significant affinity for the 5-HT1DR and 5-HT6R receptors, with Ki values of 117 nM and 170 nM, respectively. Pellotine effectively decreases intracellular cAMP levels, leading to reduced neuronal excitability and neurotransmitter release, making it a valuable tool for research into neuropharmacology and serotonergic signaling pathways.
Chemical Information
| Catalog Num | A29845 |
|---|---|
| M. Wt | 237.29 |
| Formula | C13H19NO3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 19622-05-0 |
| Synonyms | |
| SMILES | COC1=C(OC)C(O)=C(C(C)N(C)CC2)C2=C1 |
Biological Activity
| Description | Pellotine is an alkaloid that acts as an inverse agonist targeting the 5-HT7 receptor, exhibiting an EC50 of 291 nM. This compound also demonstrates significant affinity for the 5-HT1DR and 5-HT6R receptors, with Ki values of 117 nM and 170 nM, respectively. Pellotine effectively decreases intracellular cAMP levels, leading to reduced neuronal excitability and neurotransmitter release, making it a valuable tool for research into neuropharmacology and serotonergic signaling pathways. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
