Product Data Sheet
Syk Inhibitor II hydrochloride
Catalog No. A29854
Syk Inhibitor II hydrochloride is a highly selective ATP-competitive inhibitor of Syk kinase, exhibiting an IC50 of 41 nM. This compound effectively inhibits serotonin release from RBL cells, with an IC50 of 460 nM. Syk Inhibitor II hydrochloride demonstrates reduced potency against other kinases, making it a valuable tool for investigating Syk-mediated signaling pathways and exploring its anti-allergic properties in research applications.
Chemical Information
| Catalog Num | A29854 |
|---|---|
| M. Wt | 376.76 |
| Formula | C14H16ClF3N6O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2490508-82-0 |
| Synonyms | |
| SMILES | O=C(C1=CN=C(NCCN)N=C1NC2=CC=CC(C(F)(F)F)=C2)N.Cl |
Biological Activity
| Description | Syk Inhibitor II hydrochloride is a highly selective ATP-competitive inhibitor of Syk kinase, exhibiting an IC50 of 41 nM. This compound effectively inhibits serotonin release from RBL cells, with an IC50 of 460 nM. Syk Inhibitor II hydrochloride demonstrates reduced potency against other kinases, making it a valuable tool for investigating Syk-mediated signaling pathways and exploring its anti-allergic properties in research applications. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
