Product Data Sheet
Ondansetron-d3
Catalog No. A29881
Ondansetron-d3 is a deuterium-labeled analog of Ondansetron, a highly selective antagonist of the 5-HT3 receptor with an IC50 value of 103 pM. It effectively antagonizes serotonin receptors in both peripheral and central nervous systems, providing significant antiemetic activity. Ondansetron-d3 is utilized in pharmacokinetic studies to trace the metabolic pathways of Ondansetron and to explore its efficacy in preventing nausea and vomiting associated with chemotherapy and radiotherapy.
Chemical Information
| Catalog Num | A29881 |
|---|---|
| M. Wt | 296.38 |
| Formula | C18H16D3N3O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1132757-82-4 |
| Synonyms | GR 38032-d3; SN 307-d3 |
| SMILES | O=C1C2=C(CCC1CN3C(C)=NC=C3)N(C([2H])([2H])[2H])C4=CC=CC=C24 |
Biological Activity
| Description | Ondansetron-d3 is a deuterium-labeled analog of Ondansetron, a highly selective antagonist of the 5-HT3 receptor with an IC50 value of 103 pM. It effectively antagonizes serotonin receptors in both peripheral and central nervous systems, providing significant antiemetic activity. Ondansetron-d3 is utilized in pharmacokinetic studies to trace the metabolic pathways of Ondansetron and to explore its efficacy in preventing nausea and vomiting associated with chemotherapy and radiotherapy. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
