Product Data Sheet
SB-247853
Catalog No. A29888
SB-247853 is a highly selective antagonist of the 5-HT2c receptor, which plays a crucial role in various physiological processes, including cardiovascular regulation. Research has demonstrated that SB-247853 can induce orthostatic intolerance during head-up tilting, highlighting its potential impact on cardiovascular responses. This compound is valuable for studying mechanisms underlying cardiovascular diseases and the role of serotonin receptor modulation in these conditions.
Chemical Information
| Catalog Num | A29888 |
|---|---|
| M. Wt | 428.41 |
| Formula | C22H19F3N4O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 200711-10-0 |
| Synonyms | |
| SMILES | O=C(N1CCC2=C1C=C(C(F)(F)F)C(C)=C2)NC3=CC=C(OCC4=NC=CC=C4)N=C3 |
Biological Activity
| Description | SB-247853 is a highly selective antagonist of the 5-HT2c receptor, which plays a crucial role in various physiological processes, including cardiovascular regulation. Research has demonstrated that SB-247853 can induce orthostatic intolerance during head-up tilting, highlighting its potential impact on cardiovascular responses. This compound is valuable for studying mechanisms underlying cardiovascular diseases and the role of serotonin receptor modulation in these conditions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
