Product Data Sheet
5-Benzyloxytryptamine
Catalog No. A29900
5-Benzyloxytryptamine is a selective partial agonist of the 5-hydroxytryptamine 1D/1B (5-HT1D/1B) receptors, exhibiting an IC50 of 40 nM for bovine caudate 5-HT1D, with significantly lower affinity for 5-HT2 receptors (IC50 > 470 nM). This compound effectively inhibits adenylate cyclase, leading to a decrease in neurotransmitter release and downregulation of cAMP signaling. 5-Benzyloxytryptamine is valuable for the study of neurotransmitter imbalance-related disorders, particularly in research related to migraines.
Chemical Information
| Catalog Num | A29900 |
|---|---|
| M. Wt | 266.34 |
| Formula | C17H18N2O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 20776-45-8 |
| Synonyms | 5-BT |
| SMILES | NCCC1=CNC2=CC=C(OCC3=CC=CC=C3)C=C12 |
Biological Activity
| Description | 5-Benzyloxytryptamine is a selective partial agonist of the 5-hydroxytryptamine 1D/1B (5-HT1D/1B) receptors, exhibiting an IC50 of 40 nM for bovine caudate 5-HT1D, with significantly lower affinity for 5-HT2 receptors (IC50 > 470 nM). This compound effectively inhibits adenylate cyclase, leading to a decrease in neurotransmitter release and downregulation of cAMP signaling. 5-Benzyloxytryptamine is valuable for the study of neurotransmitter imbalance-related disorders, particularly in research related to migraines. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
