Product Data Sheet

Adatanserin

Catalog No. A29904

main product photo
Adatanserin is a selective partial agonist of the 5-HT1A receptor, exhibiting a high affinity with a Ki value of 1 nM. Additionally, it acts as a moderate-affinity antagonist at the 5-HT2 receptor with a Ki of 73 nM. This compound demonstrates pronounced anxiolytic and antidepressant effects in preclinical animal models, making it a valuable tool for research in anxiety and mood disorders.
Chemical Information
Catalog NumA29904
M. Wt369.50
FormulaC21H31N5O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.127266-56-2
SynonymsWY-50324; SEB-324
SMILESO=C(NCCN1CCN(CC1)C2=NC=CC=N2)C34CC(CC(C4)C5)CC5C3
Biological Activity
DescriptionAdatanserin is a selective partial agonist of the 5-HT1A receptor, exhibiting a high affinity with a Ki value of 1 nM. Additionally, it acts as a moderate-affinity antagonist at the 5-HT2 receptor with a Ki of 73 nM. This compound demonstrates pronounced anxiolytic and antidepressant effects in preclinical animal models, making it a valuable tool for research in anxiety and mood disorders.
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SHIPPING AND STORAGE
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