Product Data Sheet
RS-102221
Catalog No. A29937
RS-102221 is a selective antagonist of the 5-HT2C receptor, exhibiting a Ki value of 10 nM. This compound demonstrates significant selectivity, being nearly 100-fold more effective against the 5-HT2C receptor compared to the 5-HT2A and 5-HT2B receptors. RS-102221 has been shown to promote the differentiation of new nerve cells and is associated with increased food intake and weight gain in rat models, making it a valuable tool for research in neurobiology and metabolic studies.
Chemical Information
| Catalog Num | A29937 |
|---|---|
| M. Wt | 612.62 |
| Formula | C27H31F3N4O7S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 185376-97-0 |
| Synonyms | |
| SMILES | O=S(C1=CC=C(C(F)(F)F)C=C1)(NC2=CC(C(CCCCN(CC3)CCC3(NC(N4)=O)C4=O)=O)=C(OC)C=C2OC)=O |
Biological Activity
| Description | RS-102221 is a selective antagonist of the 5-HT2C receptor, exhibiting a Ki value of 10 nM. This compound demonstrates significant selectivity, being nearly 100-fold more effective against the 5-HT2C receptor compared to the 5-HT2A and 5-HT2B receptors. RS-102221 has been shown to promote the differentiation of new nerve cells and is associated with increased food intake and weight gain in rat models, making it a valuable tool for research in neurobiology and metabolic studies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
