Product Data Sheet
Spiramide
Catalog No. A29991
Spiramide is a potent and selective antagonist of the 5-HT2 receptor and dopamine D2 receptor, demonstrating Ki values of 2 nM and 3 nM, respectively. It exhibits over 2000-fold selectivity for the 5-HT2 receptor compared to the 5-HT1C receptor (Ki = 4300 nM). Due to its pharmacological properties, Spiramide is valuable for research applications in the fields of neuropharmacology and the study of antipsychotic mechanisms.
Chemical Information
| Catalog Num | A29991 |
|---|---|
| M. Wt | 383.46 |
| Formula | C22H26FN3O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 510-74-7 |
| Synonyms | AMI-193 |
| SMILES | O=C1NCN(C2=CC=CC=C2)C13CCN(CCCOC4=CC=C(F)C=C4)CC3 |
Biological Activity
| Description | Spiramide is a potent and selective antagonist of the 5-HT2 receptor and dopamine D2 receptor, demonstrating Ki values of 2 nM and 3 nM, respectively. It exhibits over 2000-fold selectivity for the 5-HT2 receptor compared to the 5-HT1C receptor (Ki = 4300 nM). Due to its pharmacological properties, Spiramide is valuable for research applications in the fields of neuropharmacology and the study of antipsychotic mechanisms. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
